Philanthropos TherapeuticsCOLUMBUS, OHIO

Developing an investigational oral antiviral for Lassa fever

Philanthropos Therapeutics LLC is a biotechnology company based in Columbus, Ohio.

About

Philanthropos Therapeutics LLC is a biotechnology company based in Columbus, Ohio. The company is focused on the development of LHF-535, an investigational antiviral drug candidate for Lassa fever.

Our Mission

Our mission is to develop innovative medicines that address urgent medical needs in underserved populations worldwide, including underrepresented groups in developed countries, to advance health equity and improve access to care for all.

Our Program: LHF-535

Lassa fever

Lassa fever is an acute viral illness caused by Lassa virus, a member of the arenavirus family. It is known to be endemic in several West African countries, including Nigeria, Sierra Leone, Liberia and Guinea. According to the World Health Organization, there is currently no antiviral drug approved for Lassa fever.

LHF-535

LHF-535 is an investigational small-molecule antiviral, taken by mouth, that is being developed for the potential treatment of Lassa fever. It was originally developed by Kineta, Inc. In 2025, Philanthropos Therapeutics acquired the LHF-535 program assets from Kineta.

LHF-535 has completed Phase 1 clinical studies in healthy adult volunteers (see, for example, ClinicalTrials.gov NCT03993704, sponsored by Kineta). Further clinical development will be required.

LHF-535 is an investigational drug. It has not been approved by the U.S. Food and Drug Administration (FDA) or any other regulatory authority, and its safety and effectiveness have not been established. Philanthropos Therapeutics is not currently recruiting participants for any clinical trial.

Team

Krissi Bosworth, Managing Partner

Contact

Philanthropos Therapeutics LLC
Columbus, Ohio, USA

Krissi Bosworth, Managing Partner
Philanthropos Therapeutics
Email: [email protected]

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